Searchable abstracts of presentations at key conferences in endocrinology

ea0003oc17 | Growth Regulation | BES2002

The identification of cryptic gene sequences that encode putative ligands: The example of POP1

Baird A , Burg M , Jensen-Pergakes K , Ravey P , Gonzalez A , Larocca D

A small subset of genes in the human genome encode peptides that have intrinsic therapeutic value. These genes, collectively known as the "theratome", most often encode ligands and are of particular interest to endocrinology. The genes encoding growth hormone, somatostatin, erythropoeitin, neuropeptides, placental and pituitary hormones are all examples of the theratome. Unfortunately, the sequences encoding many ligands are not always detectable within the sequences of their ...